منابع مشابه
Innate Immune Responses in Leprosy
Leprosy is an infectious disease that may present different clinical forms depending on host immune response to Mycobacterium leprae. Several studies have clarified the role of various T cell populations in leprosy; however, recent evidences suggest that local innate immune mechanisms are key determinants in driving the disease to its different clinical manifestations. Leprosy is an ideal model...
متن کاملMicronutrients influencing the immune response in leprosy.
Leprosy is a chronic infectious disease caused by Mycobacterium leprae, an intracellular bacillus of airborne transmission. The disease affects the skin and peripheral nerves and can cause neurological sequelae. The bacillus multiplies slowly in the host and the disease probably occurs due to malfunctioning in host immune response. This review addresses the role of some specific micronutrients ...
متن کاملImmunoblotting and the immune response to leprosy.
Immunoblotting has provided a powerful and effective approach to dissection of the immune response to mycobacterial antigens in a situation in which the availability of isolated antigenic components is severely limited. The basic approach of blotting on to a solid-phase support has been used in combination with SDS/polyacrylamide-gel electrophoresis, t.l.c., recombinant DNA technology and T-cel...
متن کاملImmune reconstitution inflammatory syndrome in an HIV seropositive leprosy patient.
The natural course of leprosy co-infected with human immunodeficiency virus (HIV) is not clearly understood. This is important because of the high and increasing prevalence of HIV infection in many leprosy endemic populations. – 3 The introduction of highly active antiretroviral therapy (HAART) has led to the emergence of a new clinical syndrome known as immune reconstitution inflammatory syndr...
متن کاملEffect of treatment on immune responsiveness in lepromatous leprosy patients.
This study was performed in order to analyse whether the immune unresponsiveness to Mycobacterium leprae, largely seen in lepromatous patients, persisted after discharge from treatment. Lymphoproliferation and skin tests were performed using two mycobacterial antigens (M. leprae and BCG) in three groups of lepromatous patients grouped by treatment status. Forty-seven per cent of the lepromatous...
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ژورنال
عنوان ژورنال: Indian Journal of Dermatology
سال: 2009
ISSN: 0019-5154
DOI: 10.4103/0019-5154.55626